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Search Results for " psd 95 "

Targets

14

Compounds

1

Natural Products

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T13112L1 Tat-NR2B9c acetate Tat-NR2B9c acetate (500992-11-0 Free base),NA-1 acetate Others
Tat-NR2B9c acetate (NA-1 acetate) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c acetate disrupts the PSD-...
T13112 Tat-NR2B9c Tat-NR2Bct,NA-1 NO Synthase , iGluR
Tat-NR2B9c (NA-1) is a postsynaptic density-95 (PSD-95) inhibitor with neuroprotective and antiepileptic effects.Tat-NR2B9c inhibits PSD-95d2, PSD-95d1, and PSD-95, which prevents the activation of NMDA-induced NADPH oxi...
T17293 ZL006 NMDAR , iGluR
ZL006 is an effective inhibitor of nNOS/PSD-95 interaction. ZL006 also inhibits NMDA receptor-mediated NO synthesis.
T7355 IC87201 Others , iGluR
IC87201 is a nNOS-PDZ/PSD-95-PDZ inhibitor. IC87201 showed great promise in cellular experiments and animal models of ischemic stroke and pain.
T13112L Tat-NR2B9c TFA NA-1 (TFA) Others
Tat-NR2B9c TFA is a 20-aa peptide, and acts as an inhibitor of postsynaptic density-95 (PSD-95)(EC50 of 6.7 nM for PSD-95d2), and possesses neuroprotective efficacy.
T35924 Tat-NR2Baa Tat-NR2Baa
Tat-NR2BAA is an inactive control peptide of Tat-NR2B9c. It shares a similar sequence with Tat-NR2B9c, but possesses a double-point mutation in the COOH terminal tSXV motif. This mutation renders Tat-NR2BAA unable to bin...
T75838 PDZ1 Domain inhibitor peptide TFA
PDZ1 Domain Inhibitor Peptide TFA, a cyclic peptide featuring a β-Ala lactam side chain linker, specifically targets the PDZ1 domains of postsynaptic density protein 95 (PSD-95). It effectively disrupts the GluR6/PSD-95 ...
T70232 3,4-Dephostatin
3,4-Dephostatin is an inhibitor of the interactions of CFTR-associated ligand (CAL) and PSD-95/Dlg1/ZO-1 (PDZ) domain.
TP2208 PDZ1 Domain inhibitor peptide Others
Novel cyclic peptide that disrupts interaction between GluR6 and PSD-95
T69658 Ethyl-3,4-dephostatin
Ethyl-3,4-dephostatin is a novel inhibitor of the interactions of CFTR-associated ligand and PSD-95/Dlg1/ZO-1 domain.
T76069 Tat-NR2Baa TFA
Tat-NR2BAA TFA serves as the inactive control peptide for Tat-NR2B9c, featuring a comparable sequence with a crucial distinction: a double-point mutation in its COOH-terminal tSXV motif. This alteration renders Tat-NR2BA...
T28736 SCR-4026
SCR-4026 is an inhibitor of the nNOS-PSD-95 interaction with neuroprotective activities. SCR-4026 also promotes neural stem cells to differentiate into neurons-like cells.
T35789 Palmitic acid-1-13C
Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plas...
T35791 Palmitic acid-13C
Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid i...
Cat No. Product Name Synonyms Targets
T2S0389 Emodin-1-O-β-D-glucopyranoside Emodin-1-O-glucoside Others
1. Emodin-1-O-β-D-glucopyranoside (Emodin-1-O-glucoside) has neuroprotective and uncoupling activities, and that it may be the a new uncoupler of nNOS-PSD-95. 2. Emodin-1-O-β-D-glucopyranoside shows inhibitory effects on...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00652 PSD-95 Protein, Rat, Recombinant (His) Rat E. coli
Disks large homolog 4(DLG4) is a cell membrane protein and it is a member of the membrane-associated guanylate kinase (MAGUK) family. The protein contains 1 guanylate kinase-like domain,3 PDZ (DHR) domains and 1 SH3 dom...
TMPY-03750 CRIPT Protein, Human, Recombinant (His) Human E. coli
CRIPT, also known as cysteine-rich PDZ-binding protein, belongs to the CRIPT family. It interacts with TUBB1. CRIPT also interacts strongly with the PDZ3 domain of members of the DLG4 family. It is involved in the cytosk...
TMPK-00798 IGSF11 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Immunoglobulin superfamily member 11 (IgSF11), a homophilic adhesion molecule that preferentially expressed in the brain, is a dual-binding partner of the postsynaptic scaffolding protein PSD-95 and AMPA glutamate recept...
TargetMol